Safe Upper Limit of 10,000 I.U. for Vitamin D is Suggested by New Risk Assessment Review.

Researchers from the Council for Responsible Nutrition (CRN), Mount Sinai Hospital, Toronto, and Creighton University, Omaha, NE, conducted a review of human clinical trials of vitamin D to reassess the current Tolerable Upper Intake Level (UL) for vitamin D. The review applied the risk assessment methodology employed by the Food and Nutrition Board (FNB) to derive the UL, to determine a revised safe UL in light of research conducted since 1997, when the current UL of 2000 I.U. was established. The study was published in the January 2007 issue of the American Journal of Clinical Nutrition (85, 1:6-18, 2007).

New benefits of vitamin D supplementation, beyond bone health, have continued to be discovered since the current UL was established in 1997. CRN researchers felt that the current UL was outdated and not based on current evidence; they viewed it as too restrictive, curtailing research, commercial development, and optimum nutrition policy.

The review applied FNB risk assessment methodology to relevant, well-designed human clinical trials of vitamin D conducted since 1997. Collectively, the absence of toxicity in the trials reviewed lead researchers to conclude that a supplement of 10,000 IU of vitamin D3 daily is a safe UL.

Vitamin D3 5000 provides Vitamin D3, cholecalciferol, natural vitamin D from fish liver oil. Take Vitamin D3 5000 as a dietary supplement, one or two capsules daily. Consider reducing supplementation during times of abundant sun exposure.